Contents
The purpose of the course is to deepen the participants' knowledge of the chemistry of biological molecules. It includes a detailed description of the chemistry and function of proteins and nucleic acids. The following topics are included: Components of translation and of molecular mechanisms; aminoacyl tRNA synthetases; ribosome structure; structure of rRNA and tRNA; genetic recombination; regulation of transcription; processing of RNA; posttranslational modification of proteins; proteases; selected examples of gene families; the organisation, structure and topology of DNA; nucleic acid-protein interactions; chemical modifications of nucleic acids, RNA combinatorial methods, splicing of RNA, retrovirel RNA.
Text-books
Nucleic Acids in Chemistry and Biology, ed. by G. Michael Blakburn and Michael J. Gait, Oxford University Press.
Evaluation
Study group, oral examination.
ECTS-credits
5
Semester
Spring