Syntetisk Metodologi i Total Syntese
Contents
In this course we will analyze the total synthesis of a diverse number of structurally different natural compounds. Discussions will include the types of synthetic approaches employed, including key chemical reactions and reagents used in the synthesis. Important organic transformations such as pericyclic, ionic and radical reactions will be covered, where emphasis will be made on the mechanisms, selectivity and stereochemistry. Participants in this course will be assigned to analyze a minimum of one total synthesis during the class lectures.
Teaching material
Classics in Total Synthesis, K.C. Nicolaou and E.J. Sorensen, VCH Publishers, Weinheim, 1996.
Teaching curriculum
Four hours of lectures/exercises per week.
Requirements
Four years of study including the minor subject of chemistry.
Evaluation
Pass/fail based on participation and presentations of assigned syntheses in the lectures.
Study points
5 ECTS credits. - Fall term 2003.
Teacher
Mikael Bols.
Remark
The course is offered as a course for Ph.D. students in chemistry.