STADS is once again up and running, and you can register for spring classes and exams. The registration deadline is Thursday 7 November at 23.59.
Before any work process involving chemicals can begin, you should make sure you have a plan for carrying out the work that ensures it can be performed in a way that protects everyone’s health and safety. You must write a lab protocol, and if there are hazardous chemicals involved, you must also carry out a chemical risk assessment for the entire process. Carrying out a chemical risk assessment will draw your attention to the dangerous processes involved in the experiment, in other words the steps in an experiment where you need to protect yourself and other people in the lab from exposure.
One of the first things you should investigate is whether there’s an alternative chemical that’s less hazardous or more green. Chemical manufacturing is energy and carbon-intensive, but we can’t do without chemicals: they are also the building blocks of the products that are necessary for a circular, climate-neutral economy.
Chemical manufacturers are constantly optimizing their processes to produce alternatives, and can also offer ‘green chemicals’.
When you’re searching for information from manufacturers/suppliers, you can search under ‘green chemistry’ or ‘sustainability’ to find out what ‘green’ chemicals they offer.
Green chemicals are produced on the basis of the ‘12 principles of green chemistry’ developed by Paul T. Anastas and John C. Warner in 1991. Some of the main principles are:
Examples | ||
Chemical: | Substitute: | Explanation: |
Dichlormethane (DCM) | 2-Methyltetrahydrofuran (2-MeTHF) VWR® GREEN SOLVENTS | 2-MeTHF is derived from natural raw materials like maize and sugar. |
Tetrahydrofuran (THF) | 2-Methyltetrahydrofuran (2-MeTHF) VWR® GREEN SOLVENTS | 2-MeTHF is derived from natural raw materials like maize and sugar. |
Diethyl ether | Cyclopentyl methyl ether (CPME) VWR® GREEN SOLVENTS | CPME can be synthesised from biomass, low formation of peroxides - more stable. |
Glycerol | Bio-based glycerol | Bio-based glycerol is derived from rape seed and is 100% biodegradable. |
Ethanol | Bio-based ethanol | Bio-based ethanol is derived from natural raw materials like maize and sugar. It’s production is safer for the environment. |
Ethyl acetate | Ethyl(-)-L-Lactate | Ethyl(-)-L-Lactate is less toxic and is 100% biodegradable. |
Acetone | Ethyl(-)-L-Lactate | Ethyl(-)-L-Lactate is less toxic and is 100% biodegradable. |
Acetic acid | Bio-based acetic acid Supelco® | Bio-based acetic acid is derived from by-products and residual products from the processing of regional wood and furniture. |
DMA, DMF and NMP | 1-Butylpyrrolidin-2-one | 1-Butylpyrrolidin-2-one is not subject to REACH requirements and has an inherent biodegradability. |
NA purification kit | TaqMan miRNA ABC purification kit Thermo Fischer | Traditional RNA extraction involves mercaptoethanol, phenol, chloroform and/or TRIzol, as well as producing quite a bit of plastic waste. TaqMan miRNA is a green kit that does not use dangerous chemicals and produces less plastic waste. |
Ethidium bromide | SYBR® Green, SYBR® Red, SYBR® Safe, SYBR® Gold and similar | Ethidium bromide is a carcinogen, unlike the alternatives. You can avoid using a fume hood if you use non-hazardous chemicals, as long as no other hazardous chemicals are involved in the process. |
Finding substitutes can be a long, difficult process. For example, standardised methods, descriptions in articles, etc. can make it difficult to use an alternative chemical.
Here are seven steps to help you find good substitutes:
1 | Overview of chemicals and needs |
2 | Make a plan |
3 | Search for less hazardous chemicals |
4 | Compare and assess |
5 | Test |
6 | Implementation and optimisation |
7 | Communication |
It is important that you buy chemicals from the companies with which AU has entered into a purchasing agreement, as the suppliers have committed themselves to specific climate and sustainability-related requirements.
Only buy the quantity of chemicals you will be using. Even though it may be cheaper to buy a larger quantity, this may ultimately turn out to be more expensive financially and environmentally, as the chemical may just end up sitting on the shelf and being disposed as chemical waste after few years.
Buying a pre-mixed solution rather than buying a hazardous chemical in a large quantity can be safer and greener. For example, it’s a good idea to buy a 0.1 M sodium azide solution instead of buying 100 grams of sodium-azide and mixing the solution yourself.
Chemicals at AU are registered in the chemical database Kiros. In this database, you can search for a chemical and then ask the group(s) within your own department that have the chemical registered in Kiros to borrow or use the chemical for a small experiment rather than purchasing a new container.
You can only borrow/lend chemicals within your own department or where an agreement has been made. We don’t have the staff to handle lending and delivery to everyone – please consider that when you borrow chemicals.
When you search for a chemical, the registered groups can be seen under ‘Resources’. You can read more in the quick guide to Kiros, which you will find under ‘Guidances’ at www.kiros.dk – you log on with your AU login.