desværre

Pt. ingen dansk version

 

Physical Biochemistry/Fysisk biokemi

 

Homepage of the course

http://bionmr1.chem.au.dk/fysisk_biokemi/

 

Code

 

Credits

10 ECTS

 

Aim

The course aims at giving the student an elementary insight into the basic principles and the applications of common physical methods in biochemistry and molecular biology.

 

Contents

Based on general principles of protein structure, interactions, and thermodynamics, the course describes a variety of methods for separation and characterization of biological macromolecules. This includes chromatography, electrophoresis, mass spectrometry, various kinds of spectroscopies (electronic and vibrational absorption), linear and circular dichroism, fluorescence spectroscopy, X-ray diffraction, and nuclear magnetic resonance (NMR) spectroscopy. High priority is devoted to comparison of the various methods, highlighting their applicability, interplay and complementary role for characterization of biological macromolecules.

 

Term

1^st and 2^nd quarter

 

Prerequisites

1^st year on any of the studies in molecular biology

 

Type of classes

42 lectures

42 theoretical exercises, demonstrations, and laboratory exercises.

 

Type of evaluation and aids

4 hour exam without aids, evaluated on basis of passing/not passing with internal examiner.

 

Educational materials

Textbook: PRINCIPLES OF PHYSICAL BIOCHEMISTRY, (1998)

Authors: van Holde, Johnson, and Ho

Publishing house: Prentice Hall, New Jersey

ISBN No: 0-13-720459-0

 

Supplementary material

Laboratory manual

 

Responsible teacher

Name: Niels Chr. Nielsen

Office address: Building 112, room 113, Department of Chemistry

Phone no: +45 8942 3841

E-mail: ncn@imsb.au.dk

 

Other teachers

Thomas Vosegaard, Anders Malmendal, Kim Kusk Mortensen , and Lars Sottrup-Jensen

 

Max participants

No limit

 

Language

Material: English

Spoken language: Danish