Contents
This course contains the description of the general structure of proteins, polysaccharides and nucleic acids as well as their conformation and folding. The chemical and physical properties wich are of importance for the structure and interactions of these macromolescules will be
studied. The properties of macromolecules in solution and their interactions in solution and in crystals are described.
The structure and function of examples from essential areas of biochemistry will be enlightened by the use of PC based display programmes during computer exercises. Possible examples will be enzymatic reactions, proteolytic enzymes and their inhibitors, immunoglobulins, vira, binding of nucleotides, protein/nucleic acid complexes, control of transscription, DNA and RNA.
Textbooks
T.E. Creighton: "Proteins, Structures and Molecular Properties". 2nd Edition, 1993. W. H. Freeman, New York.
C. Branden & J. Tooze: "Introduction to Protein Structure". 2nd Edition, 1999. Garland Publishung Inc., New York.
Hand-outs
Original literature.
Evaluation
Written examination (13-scale).
ECTS-credits
10
Semester
Spring