Infection and inflammation
The Bachelor and Master projects within the 'Infection and Inflammation' research theme cover a broad spectrum of disciplines, including infection biology, medicine, and immunology, and target a wide variety of diseases.
Areas of focus include brain infections and inflammation, acute viral and bacterial infections, rheumatic conditions, and cancer. Importantly, recent breakthroughs have highlighted the involvement of the immune system in numerous diseases previously not considered related to immunology.
Project on Cardiovascular Inflammation
Short description
Deciphering the Role and Function of Blood Vessels in Pathophysiological States.
Keywords
Vascular biology
Inflammation
Cancer
Obesity
Project on Human Skin Microbiome
Quest for causality: The role of the human microbiome in sarcoidosis (Mikrobiomets betydning for udvikling af sarkoidose)
The cause of sarcoidosis is still unknown. This project investigates the contribution of the human lung and skin microbiome in disease pathogenesis.
Workplace: Center for Rare Lung Diseases, Department of Respiratory Diseases and Allergy/AUH & Dept. of Biomedicine/AU
Supervisors: Prof. Elisabeth Bendstrup & Assoc Prof. Holger Brüggemann
Keywords
Microbiome
Acne vulgaris
Implant-associated infections
Skin probiotics
Project on Multiple Sclerosis
Keywords
Multiple sclerosis
Immunology
Virology
Project on Bacterial Functional Amyloids
Description
The infectivity of several pathogenic bacteria is tightly associated with biofilm formation mediating resistance to host immune response and antibiotics. The structural component of biofilms is functional bacterial amyloids (FuBA). The Andreasen lab focuses on understanding the molecular mechanisms involved in the formation of FuBA such as interactions between FuBA and small molecules, lipid bilayers and surfaces. We use an interdisciplinary approach employing fluorescence plate reader assays, structural characterization and morphological studies using electron microscopy. If you are interested, please contact Maria Andreasen, mariaj@biomed.au.dk.
Keywords
Functional amyloids
Protein aggregation
Bacterial biofilms
Protein self-assembly
Project on Cancer Metabolism
Keywords
Pancreatic cancer
Iron
Glycosylation
Metabolism
Project on Cancer biology applying CRISPR
Keywords
In vivo samples
CRISPR
Generation of CRISPR-edited cell clones
Histology
Bioinformatics